Theres no clear understanding of why adequate levels of B12 are associated with a reduced risk of obesity, but there are a few theories 9-11 : B12 may influence how the body stores fat B12 is required for proper muscle protein, and low levels could interfere with recovery Insufficient B12 impairs red blood cell production and interferes with oxygen delivery to muscles Key takeaway: There is some evidence linking low B12 levels to a higher risk of obesity in children, adolescents, and adults, but the evidence is too weak to confirm a relationship
Suboptimal B12 causes brain fog, difficulty concentrating, mood changes, tingling extremities, and progressive neurological decline
Cofactor for L-methylmalonyl-coenzyme A mutase 5-Deoxyadenosylcobalamin is required by the enzyme that catalyzes the conversion of L-methylmalonyl-coenzyme A to succinyl-coenzyme A (succinyl-CoA), which then enters the citric acid cycle ( Figure 2 )
Many plaintiffs allege that the manufacturer failed to adequately warn patients and healthcare providers about the risk of severe gastrointestinal side effects, such as gastroparesis and stomach paralysis, as well as vision loss and other complications
PMID: 81 BawejaSMittalAThangariyalSSubudhiPDGautamSKaulR
GLPS, glycyrrhizin preparation
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